Impact of Systemic Lupus Erythematosus on Quality of Life in Egyptian Patients
Author Information
Author(s): Hamdy Sliem, Gamal Tawfik, Khalil A Khalil, Nagwa Ibrahim
Primary Institution: Suez Canal University
Hypothesis
SLE is a disease characterized by a variety of clinical manifestations with changes in its activity over time, and the quality of life of SLE patients during disease activity is low.
Conclusion
The quality of life of SLE patients with renal involvement is poorer than that of healthy controls in all domains except emotional limitations.
Supporting Evidence
- All domains of SF-36 were significantly lower in SLE patients compared to controls.
- 51% of SLE patients had mild disease activity.
- Significant correlations were found between disease activity and quality of life scores.
Takeaway
People with lupus often feel worse than healthy people, especially when their disease is more active, which affects their daily lives.
Methodology
A case control study involving 59 SLE patients and 20 healthy controls, measuring disease activity with SLEDAI and quality of life with SF-36.
Limitations
The study may not represent all SLE patients due to its specific demographic focus.
Participant Demographics
Mean age of 28.6 years, 94.9% female.
Statistical Information
P-Value
<0.05
Statistical Significance
p<0.05
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