Impact of Hyperthyroidism on Bone Health in Men
Author Information
Author(s): El Hadidy M, Ghonaim Mohamed, El Gawad Soma Sh Abd, El Atta Mohamed Abou
Primary Institution: Mansoura University, Egypt
Hypothesis
The study aims to evaluate the impact of severity, duration, and etiology of hyperthyroidism on bone turnover markers and bone mineral density.
Conclusion
Men with hyperthyroidism experience significant bone loss and higher biochemical markers of bone turnover.
Supporting Evidence
- Biochemical markers of bone turnover were significantly higher in patients with hyperthyroidism compared to controls.
- Bone mineral density was significantly lower in hyperthyroid patients than in controls.
- The duration of hyperthyroidism positively correlated with bone turnover markers.
Takeaway
This study found that men with hyperthyroidism have weaker bones and higher levels of substances that indicate bone loss.
Methodology
The study included 52 male patients with hyperthyroidism and 25 healthy controls, measuring bone mineral density and biochemical markers of bone turnover.
Limitations
The study excluded women and patients with certain comorbidities, which may limit the generalizability of the findings.
Participant Demographics
52 male patients aged 23 to 65 years with hyperthyroidism and 25 healthy age-matched male controls.
Statistical Information
P-Value
p<0.0001
Statistical Significance
p<0.01
Digital Object Identifier (DOI)
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