B-virus from Pet Macaque Monkeys: An Emerging Threat in the United States?
1998

B-Virus in Nonhuman Primates

Sample size: 24 publication Evidence: moderate

Author Information

Author(s): Stephanie R. Ostrowski, Mira J. Leslie, Terri Parrott, Susan Abelt, Patrick E. Piercy

Primary Institution: Centers for Disease Control and Prevention

Hypothesis

What is the prevalence and risk of B-virus infection in humans from macaque bites?

Conclusion

B-virus infection is highly prevalent in adult macaques and poses a significant health risk to humans, particularly children.

Supporting Evidence

  • B-virus infection is highly prevalent (80% to 90%) in adult macaques.
  • Four out of six tested macaques were seropositive for B-virus.
  • Children were 3.2 times more likely to be bitten than adults.
  • Symptomatic human infection with B-virus is rare but can be severe.
  • Of 24 known symptomatic patients, 19 (79%) died.

Takeaway

Macaques can carry a virus that can make people very sick, especially if they bite you, and kids are more likely to get bitten than adults.

Methodology

The study examined seven nonoccupational exposure incidents involving 24 persons and eight macaques, testing six macaques for herpes B.

Potential Biases

Owners may be reluctant to report bites, leading to underreporting of cases.

Limitations

The study is based on a limited case series and may not represent the broader population.

Participant Demographics

The study involved 24 persons, including children and adults, with a noted higher incidence of bites in children.

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