Lymphoplasmacytic Lymphoma Presenting as Severe Secondary Raynaud’s Phenomenon
2024

Lymphoplasmacytic Lymphoma and Raynaud's Phenomenon

publication Evidence: low

Author Information

Author(s): Muacevic Alexander, Adler John R, Rorah Drayton J, Daghlas Salah, Badshah Mashood, Schmidt Paul, Maz Mehrdad

Primary Institution: University of Kansas Medical Center, Kansas City, USA

Hypothesis

Can lymphoplasmacytic lymphoma cause severe secondary Raynaud's phenomenon?

Conclusion

The study emphasizes the importance of distinguishing between primary and secondary Raynaud's phenomenon to prevent poor patient outcomes.

Supporting Evidence

  • The patient was initially misdiagnosed with primary Raynaud's phenomenon.
  • His symptoms progressed to digit necrosis requiring amputation.
  • A diagnosis of type I cryoglobulinemia secondary to lymphoplasmacytic lymphoma was made.

Takeaway

This study shows that a rare type of blood cancer can cause serious problems with blood flow in fingers, which can lead to severe damage if not treated properly.

Methodology

Case report of a 77-year-old male with Raynaud's phenomenon and subsequent diagnosis of lymphoplasmacytic lymphoma.

Limitations

The study is based on a single case report, limiting generalizability.

Participant Demographics

77-year-old male with a history of coronary artery disease and other comorbidities.

Digital Object Identifier (DOI)

10.7759/cureus.74144

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