Cost-Effectiveness of Breast Cancer Screening Using Digital Mammography in Canada
Author Information
Author(s): Wilkinson Anna N. MD MSc, Mainprize James G. PhD, Yaffe Martin J. PhD, Robinson Jessica PharmD, Cordeiro Erin MD MSc, Look Hong Nicole J. MD MSc, Williams Phillip MD, Moideen Nikitha MD, Renaud Julie MSc, Seely Jean M. MD, Rushton Moira MD MPH
Primary Institution: University of Ottawa Faculty of Medicine
Hypothesis
What is the cost-effectiveness of digital mammographic screening for breast cancer?
Conclusion
The study found that earlier initiation of screening mammography at age 40 years yields substantial health care savings while improving breast cancer outcomes.
Supporting Evidence
- Biennial screening at ages 40 to 74 years was cost-saving, saving CAD$49,759 per death averted.
- Annual screening at ages 40 to 74 years achieved the best breast cancer outcomes.
- Screening at age 40 years resulted in improved clinical outcomes and reduced health care spending.
Takeaway
This study shows that starting breast cancer screening at age 40 can save money and help catch cancer earlier, which is better for health.
Methodology
The study used a microsimulation model to estimate the impact of various screening schedules on clinical outcomes and treatment costs.
Potential Biases
Potential bias due to not accounting for individual risk factors like breast density or ethnicity.
Limitations
The study did not include costs outside the public system and used average sensitivity for mammography, which may not reflect all populations.
Participant Demographics
A single birth cohort of individuals assigned female at birth in 1975 in Canada.
Digital Object Identifier (DOI)
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