Functional genomics reveals increases in cholesterol biosynthetic genes and highly unsaturated fatty acid biosynthesis after dietary substitution of fish oil with vegetable oils in Atlantic salmon (Salmo salar)
2008

Effects of Replacing Fish Oil with Vegetable Oils in Atlantic Salmon

Sample size: 250 publication 10 minutes Evidence: moderate

Author Information

Author(s): Leaver Michael J, Villeneuve Laure A N, Obach Alex, Jensen Linda, Bron James E, Tocher Douglas R, Taggart John B

Primary Institution: Institute of Aquaculture, University of Stirling

Hypothesis

What are the effects of substituting fish oil with vegetable oils on the health and metabolism of Atlantic salmon?

Conclusion

Replacing fish oil with vegetable oils in salmon diets leads to significant changes in lipid metabolism, but does not affect overall growth.

Supporting Evidence

  • Fish fed vegetable oils showed increased protein content and altered fatty acid composition.
  • Gene expression analysis revealed upregulation of cholesterol biosynthesis genes in response to vegetable oil diets.
  • Despite changes in lipid metabolism, cholesterol levels in fish remained stable.

Takeaway

This study shows that changing the type of oil in fish food can change how fish use fats, but it doesn't make them grow any bigger.

Methodology

The study used cDNA microarray analysis, lipid composition analysis, and biochemical assays to assess the effects of different vegetable oils on Atlantic salmon.

Potential Biases

Potential biases may arise from the specific conditions of the aquaculture environment and the selection of fish used in the study.

Limitations

The study was limited by the inherent variability among domesticated farmed Atlantic salmon and the short duration of the trial.

Participant Demographics

Atlantic salmon (Salmo salar) post-smolts, average weight 132 g.

Statistical Information

P-Value

p<0.05

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1186/1471-2164-9-299

Want to read the original?

Access the complete publication on the publisher's website

View Original Publication