Seizure and Hepatosplenomegaly—Rare Manifestation of Parvovirus B-19: A Case Report and Review of the Literature
2011

Rare Case of Parvovirus B19 Infection in a Child

Sample size: 1 publication Evidence: low

Author Information

Author(s): Kamlesh Yadav, Pallav Gupta, Manjula Murari, Rohan Malik

Primary Institution: Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India

Hypothesis

Can parvovirus B19 infection present with seizures and hepatosplenomegaly in a child?

Conclusion

The case highlights an unusual presentation of parvovirus B19 infection with seizures and hepatosplenomegaly in a 10-month-old child.

Supporting Evidence

  • The child presented with high-grade fever, seizures, and hepatosplenomegaly.
  • Bone marrow aspiration showed giant pro-erythroblasts consistent with parvovirus infection.
  • PCR testing confirmed the presence of parvovirus genomic sequences.

Takeaway

This study talks about a 10-month-old baby who got very sick with fever and seizures because of a virus called parvovirus B19, which is usually not known to cause these problems.

Methodology

The child underwent bone marrow aspiration, liver biopsy, and parvovirus PCR testing.

Limitations

The study is based on a single case report, limiting generalizability.

Participant Demographics

10-month-old immunocompetent male child.

Digital Object Identifier (DOI)

10.1155/2011/287914

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