Diversity of SCCmec Elements in Methicillin-Resistant Coagulase-Negative Staphylococci Clinical Isolates
Author Information
Author(s): Zong Zhiyong, Peng Chunhong, Lü Xiaoju
Primary Institution: West China Hospital, Sichuan University, Chengdu, China
Hypothesis
Characterization of SCCmec in MR-CoNS can generate useful information on the mobilization and evolution of this element.
Conclusion
SCCmec types III, IV and V were prevalent in MR-CoNS and many isolates could harbor more than one type.
Supporting Evidence
- A total of 84 MR-CoNS were collected from clinical specimens.
- SCCmec types were assigned for 63 of 84 isolates by multiplex PCR.
- Type III SCCmec was the most common type found in the study.
Takeaway
This study looked at different types of bacteria that are resistant to a common antibiotic and found that they can have many different genetic types.
Methodology
84 clinical isolates of MR-CoNS were collected and analyzed using PCR for mecA and SCCmec typing.
Limitations
Some SCCmec types could not be determined due to PCR failures.
Participant Demographics
Clinical isolates from patients at West China Hospital, Chengdu, China.
Digital Object Identifier (DOI)
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