An Analysis Pipeline for Genome-wide Association Studies
2008
Efficient Analysis Pipeline for Genome-wide Association Studies
publication
Author Information
Author(s): Stefanov Stefan, Lautenberger James, Gold Bert
Primary Institution: National Cancer Institute at Frederick
Hypothesis
We developed an efficient pipeline to analyze genome-wide association study single nucleotide polymorphism scan results.
Conclusion
The modified PB file format allows for rapid analysis and visualization of genetic data from genome-wide association studies.
Supporting Evidence
- The modified PB format consolidates SNP calls and confidence scores into a single file.
- Perl scripts were developed to facilitate the conversion and analysis of genetic data.
- The pipeline allows for quick extraction and analysis of genotype information.
Takeaway
This study created a new way to organize and analyze genetic data quickly, making it easier for researchers to understand and use.
Methodology
The study developed a modified PB file format for organizing SNP data and used various statistical tests for analysis.
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