Evaluation of the Analyte +2 Calcium Analyser in Clinical Chemistry
Author Information
Author(s): Rosemarie Freaney, Orla M. Casey, Teresa Quinn, Francis P. Muldowney
Primary Institution: Department of Metabolism & Renal Disease, St. Vincent's Hospital & Department of Medicine, University College, Dublin, Eire
Hypothesis
The Analyte +2 system provides accurate and precise measurements of serum ionized calcium and pH.
Conclusion
The Analyte +2 system is effective for rapid monitoring of serum ionized calcium and pH with minimal maintenance.
Supporting Evidence
- The Analyte +2 system showed a correlation coefficient of r 0.986 with the Orion SS 20 analyser.
- Precision for aqueous calcium solutions was below 0.5% for most measurements.
- Serum ionized calcium values remained stable for up to 48 hours at 4°C.
Takeaway
This study tested a new machine that measures calcium in blood, and it works well and is easy to use.
Methodology
The study involved comparing ionized calcium measurements from the Analyte +2 system with those from the Orion SS 20 analyser using human serum samples.
Limitations
The accuracy of the Analyte +2 system could not be fully assessed due to the lack of an absolute reference method.
Participant Demographics
29 healthy controls (12 males, 17 females, age range 20-30 years)
Statistical Information
P-Value
p<0.001
Confidence Interval
95% confidence limits 1.020 +/- 0.034 mmol/l
Statistical Significance
p<0.001
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