Lung Cancer Attributable to Indoor Radon Exposure in France: Impact of the Risk Models and Uncertainty Analysis
2006

Lung Cancer Risk from Indoor Radon in France

Sample size: 61889304 publication 10 minutes Evidence: moderate

Author Information

Author(s): Catelinois Olivier, Rogel Agnès, Laurier Dominique, Billon Solenne, Hemon Denis, Verger Pierre, Tirmarche Margot

Primary Institution: Institute for Radiation Protection and Nuclear Safety

Hypothesis

What is the lung cancer risk associated with indoor radon exposure in France?

Conclusion

Indoor radon exposure may be responsible for 2% to 12% of lung cancer deaths in France.

Supporting Evidence

  • Radon is a well-established human carcinogen and the main source of radioactivity exposure for the general population.
  • The estimated number of lung cancer deaths attributable to indoor radon exposure ranges from 543 to 3,108.
  • Smokers can reduce their risk by lowering indoor radon levels and quitting smoking.

Takeaway

Breathing in radon gas from homes can cause lung cancer, and many people in France are affected by it.

Methodology

The study used exposure-response relations from miner cohorts and residential case-control studies to estimate lung cancer deaths attributable to radon.

Potential Biases

Potential bias due to reliance on data from miners for general population risk assessment.

Limitations

The study's estimates are affected by uncertainties in exposure measurements and the interaction between radon and tobacco.

Participant Demographics

The study considered the entire French population, with demographic data from the 1999 census.

Statistical Information

Confidence Interval

90% UI: 75–1,097 to 2,996–3,221

Digital Object Identifier (DOI)

10.1289/ehp.9070

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