Prognostic Value of Stress Perfusion Cardiac MRI in Stable Coronary Artery Disease
Author Information
Author(s): Catalano Oronzo, Moro Guido, Frascaroli Mauro, Ceresa Monica, Perotti Mariarosa, Priori Silvia G, Baldi Maurizia
Primary Institution: Fondazione Salvatore Maugeri, Pavia, Italy
Hypothesis
What is the prognostic value of stress perfusion cardiac magnetic resonance in patients with stable coronary artery disease?
Conclusion
The study found no independent association between stress-induced perfusion defects at CMR and mortality, but identified stress CMR as a strong predictor of subsequent revascularization procedures.
Supporting Evidence
- 30 deaths occurred during the follow-up period of 38±21 months.
- 79 patients underwent revascularization procedures.
- SP-CMR was the strongest predictor of non-CMR related revascularization procedures.
Takeaway
Doctors used a special heart scan to see if stress affects heart blood flow in patients with stable heart disease, and found it helps predict if they will need surgery later.
Methodology
The study involved consecutive patients undergoing CMR for chronic CAD, assessing myocardial perfusion after stress and evaluating images for perfusion defects.
Limitations
The study may not apply to all patients with CAD as it focused on unselected patients and did not find a significant association with mortality.
Participant Demographics
78% males, average age 64±11 years.
Statistical Information
P-Value
p=0.009
Confidence Interval
HR 4.7 [1.7-12.9]
Statistical Significance
p<0.001
Digital Object Identifier (DOI)
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