Increasing rates of cervical cancer in young women in England: an analysis of national data 1982–2006
2011

Cervical Cancer Rates Rising in Young Women in England

Sample size: 71511 publication 10 minutes Evidence: high

Author Information

Author(s): G Foley, R Alston, M Geraci, L Brabin, H Kitchener, J Birch

Primary Institution: University of Manchester

Hypothesis

What are the trends in cervical cancer incidence among young women in England from 1982 to 2006?

Conclusion

Cervical cancer incidence in young women has increased significantly since 1992, despite an overall decline in older age groups.

Supporting Evidence

  • Overall incidence of cervical cancer fell from 213 to 112 per million person years from 1982 to 2006.
  • In women aged 20-29, incidence increased significantly by 2.2% annually from 1992 to 2006.
  • Incidence rates varied significantly by region, with the highest rates in Yorkshire and the Humber.

Takeaway

Cervical cancer is becoming more common in young women in England, even though it's less common in older women now.

Methodology

Data on cervical cancer cases from a national cancer registration database were analyzed using Poisson regression to estimate trends.

Potential Biases

Potential biases may arise from variations in screening uptake and socioeconomic factors.

Limitations

The study does not account for individual risk factors such as sexual behavior and smoking in detail.

Participant Demographics

Women aged 20-79 years diagnosed with cervical cancer in England from 1982 to 2006.

Statistical Information

P-Value

<0.001

Confidence Interval

95% CI for APC

Statistical Significance

p<0.001

Digital Object Identifier (DOI)

10.1038/bjc.2011.196

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