Diagnostic Models for Differentiating COVID-19-Related Acute Ischemic Stroke Using Machine Learning Methods
2024

Using Machine Learning to Identify COVID-19-Related Stroke

Sample size: 57 publication 10 minutes Evidence: moderate

Author Information

Author(s): Eylem Gul Ates, Coban Gokcen, Karakaya Jale

Primary Institution: Hacettepe University

Hypothesis

This study aims to evaluate the impact of COVID-19 on acute ischemic stroke using radiomic features extracted from brain MR images and machine learning methods.

Conclusion

The proposed radiomics-based classification model effectively distinguishes acute ischemic strokes associated with COVID-19 from other causes.

Supporting Evidence

  • The study included MRI data from 57 patients diagnosed with acute ischemic stroke.
  • Machine learning algorithms were used to classify strokes based on radiomic features.
  • The k-NN classifier achieved the best performance with an AUC of 0.882.

Takeaway

Researchers used brain scans to teach a computer how to tell if a stroke was caused by COVID-19 or not, helping doctors make better decisions.

Methodology

This retrospective study analyzed MRI data from 57 patients diagnosed with acute ischemic stroke, using machine learning algorithms to classify COVID-19-related strokes.

Potential Biases

The strict inclusion criteria may have introduced selection bias, affecting the representativeness of the sample.

Limitations

The study had a small sample size and was conducted at a single center, which may limit the generalizability of the findings.

Participant Demographics

The average age of participants was 60.88 years, with 30 COVID-19-positive and 27 COVID-19-negative patients; 66.7% of the COVID-19-negative group were women.

Statistical Information

P-Value

0.05

Confidence Interval

95% CI: 0.806–0.900

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.3390/diagnostics14242802

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