Childhood Sarcoidosis: A Rare but Fascinating Disorder
Author Information
Author(s): Avinash K Shetty, Abraham Gedalia
Primary Institution: Wake Forest University Health Sciences and Brenner Children's Hospital, Louisiana State University Medical Center and Children's Hospital of New Orleans
Conclusion
Childhood sarcoidosis is a rare condition that can present with various symptoms and has a poorer prognosis in early-onset cases.
Supporting Evidence
- Childhood sarcoidosis is characterized by a triad of rash, uveitis, and arthritis in early-onset cases.
- Older children usually present with multisystem disease similar to adult manifestations.
- The diagnosis is confirmed by demonstrating a typical noncaseating granuloma on a biopsy specimen.
- Current therapy of choice for multisystem involvement is oral corticosteroids.
Takeaway
Childhood sarcoidosis is a rare disease that can affect many parts of the body, and it can be more serious if it starts when kids are very young.
Methodology
This review discusses the epidemiology, pathogenesis, etiology, and clinical features of sarcoidosis in children, along with current approaches to diagnosis and treatment.
Limitations
The true incidence and prevalence of childhood sarcoidosis is unknown due to its rarity.
Participant Demographics
Most reported childhood cases have occurred in patients aged 13–15 years, with a higher incidence among African Americans.
Digital Object Identifier (DOI)
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