Antibody Responses to Malaria in Myanmar
Author Information
Author(s): Kim Tong-Soo, Kim Hyung-Hwan, Kim Jung-Yeon, Kong Yoon, Na Byoung-Kuk, Lin Khin, Moon Sung-Ung, Kim Yeon-Joo, Kwon Myoung-Hee, Sohn Youngjoo, Kim Hyuck, Lee Hyeong-Woo
Primary Institution: Department of Parasitology, College of Medicine, Inha University
Hypothesis
The study aims to investigate the profile of antibodies against Plasmodium vivax and Plasmodium falciparum in residents of Mandalay, Myanmar.
Conclusion
Sero-diagnosis is not helpful to discriminate between malaria patients and symptomatic individuals during the epidemic season in Myanmar.
Supporting Evidence
- 14 patients were infected with P. vivax and 26 with P. falciparum by thick smear examination.
- The positivity rate of the PvCSP VK210 subtype was higher in symptomatic individuals than in those confirmed positive by microscopy.
- The positive rates for blood stage antigens of P. falciparum were higher in patients confirmed by microscopy.
Takeaway
The study looked at how people's bodies respond to malaria and found that just having antibodies doesn't mean someone is sick.
Methodology
The study used microscopic examination and serological tests (IFAT and ELISA) to analyze blood samples from patients.
Limitations
The study may not adequately represent the entire population due to the limited geographic area and sample size.
Participant Demographics
Residents of Mandalay, Myanmar, with clinical symptoms associated with malaria.
Digital Object Identifier (DOI)
Want to read the original?
Access the complete publication on the publisher's website