Clinical outcome and risk factors for recurrence in borderline ovarian tumours
Author Information
Author(s): Yokoyama Y, Moriya T, Takano T, Shoji T, Takahashi O, Nakahara K, Yamada H, Yaegashi N, Okamura K, Izutsu T, Sugiyama T, Tanaka T, Kurachi H, Sato A, Tase T, Mizunuma H
Primary Institution: Tohoku Gynecologic Cancer Unit
Hypothesis
What are the long-term prognosis and risk factors for recurrence in borderline ovarian tumours?
Conclusion
The long-term prognosis of borderline ovarian tumours is favourable, with no tumour-related deaths reported.
Supporting Evidence
- 90.6% of cases were at clinical stage I.
- Recurrence was found in eight cases, but no tumour-related deaths were reported.
- The 10-year disease-free survival rate was 89.1% for the radical surgery group and 57.4% for the conservative surgery group.
- Serous type and conservative surgery were found to be important variables affecting recurrence.
Takeaway
This study looked at women with borderline ovarian tumours and found that while some had recurrences, most did well and didn't die from the disease.
Methodology
A retrospective analysis of 121 borderline ovarian tumour cases treated between 1994 and 2003, examining clinical stage, histopathological subtype, surgical technique, and recurrence.
Potential Biases
Potential bias due to the retrospective nature of the study and lack of uniformity in chemotherapy regimens.
Limitations
Surgical staging was not considered beforehand in all cases, which may introduce bias.
Participant Demographics
Median age of participants was 43 years, with 42.1% below 40 and 24.0% above 60.
Statistical Information
P-Value
p<0.05
Confidence Interval
0.02–0.52
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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