Out-of-Hospital Cardiac Arrest and Airborne Fine Particulate Matter: A Case–Crossover Analysis of Emergency Medical Services Data in Indianapolis, Indiana
2008

Impact of Air Pollution on Cardiac Arrests

Sample size: 1374 publication 10 minutes Evidence: moderate

Author Information

Author(s): Frank S. Rosenthal, John P. Carney, Michael L. Olinger

Primary Institution: Purdue University

Hypothesis

Does short-term exposure to PM2.5 increase the risk of out-of-hospital cardiac arrest (OHCA)?

Conclusion

Short-term PM2.5 exposure appears to increase the risk of out-of-hospital cardiac arrests, particularly in certain demographic groups.

Supporting Evidence

  • PM2.5 exposure on the day of the arrest increased OHCA risk for bystander-witnessed cases.
  • Significant HRs were found for white subjects and those aged 60-75 years.
  • Risk increased with PM2.5 exposure during the hour of the arrest.

Takeaway

Breathing in tiny particles from the air can make some people have heart problems, especially older folks or those with certain heart rhythms.

Methodology

A case–crossover analysis was used to compare hourly and daily PM2.5 exposures with recorded OHCAs.

Potential Biases

Potential biases due to imprecise exposure estimates and lack of information on co-pollutants.

Limitations

The study had a small number of cases and lacked detailed information on the causes of cardiac arrests.

Participant Demographics

Participants included individuals experiencing OHCA, with a mean age of 60.4 years, predominantly white and male.

Statistical Information

P-Value

<0.05

Confidence Interval

1.01–1.25

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1289/ehp.10757

Want to read the original?

Access the complete publication on the publisher's website

View Original Publication