A Chinese Herbal Medicine, Tokishakuyakusan, Reduces the Worsening of Impairments and Independence after Stroke: A 1-Year Randomized, Controlled Trial
2011

Tokishakuyakusan Herbal Medicine Helps Stroke Patients

Sample size: 31 publication Evidence: moderate

Author Information

Author(s): Hirozo Goto, Nobuhiko Satoh, Yoshinori Hayashi, Hiroaki Hikiami, Yutaka Nagata, Ryosuke Obi, Yutaka Shimada

Primary Institution: University of Toyama

Hypothesis

Does Tokishakuyakusan improve impairments and independence in post-stroke patients over a 12-month period?

Conclusion

Tokishakuyakusan was found to suppress the worsening of impairments and independence in post-stroke patients.

Supporting Evidence

  • Impairments in the TS group did not significantly change, while they worsened in the control group.
  • Independence according to FIM did not change significantly in the TS group, but worsened in the control group.
  • TS was effective in suppressing impairments of lower limbs and improving visuospatial perception.

Takeaway

This study shows that a special herbal medicine can help people who had a stroke feel better and stay more independent.

Methodology

A 12-month randomized, controlled trial with assessments using the Stroke Impairment Assessment Set (SIAS) and Functional Independence Measure (FIM).

Potential Biases

Potential bias due to lack of blinding for the treatment group.

Limitations

The study had a small sample size and lacked a placebo control.

Participant Demographics

31 post-stroke patients (9 men and 22 women) with a mean age of 81.4 years.

Statistical Information

P-Value

p<0.05

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1093/ecam/nep026

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