Human breast cancer and sexual activities
2008

Human Breast Cancer and Sexual Activities

publication Evidence: moderate

Author Information

Author(s): Akil N, Kassab A, Yasmeen A, Darnel A D, Bismar T A, Al Moustafa A-E

Primary Institution: Lady Davis Institute for Medical Research of the Sir Mortimer B Davis-Jewish General Hospital, McGill University

Hypothesis

HPVs could be transmitted to the breast through sexual activities.

Conclusion

High-risk HPV-positive breast cancers are more frequent in younger women who are probably sexually more active than older women.

Supporting Evidence

  • High-risk HPVs are present in more than 50% of human breast cancers.
  • HPVs of the same type were found in both cervical and breast cancer of the same patients.
  • The average age of HPV-positive breast cancer in Greek and Australian women is lower than that of HPV-negative breast cancer.

Takeaway

This study suggests that having high-risk HPV infections might be linked to being sexually active, which could lead to breast cancer in younger women.

Methodology

The study compared the average ages of women with HPV-positive and HPV-negative breast cancers.

Limitations

Future epidemiological studies are necessary to confirm these findings.

Participant Demographics

The study involved young Canadian and Syrian women.

Statistical Information

P-Value

0.05

Statistical Significance

p=0.05

Digital Object Identifier (DOI)

10.1038/sj.bjc.6604103

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