Cardiac Protection from Red Millet Yellow Wine
Author Information
Author(s): He Zehui, Zhou Yu, Li Shuang, Li Wen, Zhang Yingxin, Guo Cancan, Guo Zexin, Wei Bo, Bi Yuefeng, Bazinet Laurent
Primary Institution: School of Pharmaceutic Sciences, Zhengzhou University
Hypothesis
Red millet yellow wine contains bioactive peptides that can protect cardiac cells from oxidative stress.
Conclusion
Red millet yellow wine has significant cardioprotective effects, primarily due to its bioactive peptides that enhance antioxidant capacity.
Supporting Evidence
- Red millet yellow wine contains high levels of bioactive peptides.
- Peptides from red millet yellow wine improved cell viability in oxidative stress models.
- The antioxidant effects were linked to the activation of the Sirt1/Nrf2 pathway.
- Peptides were isolated with a yield of 72.23% using optimized extraction methods.
Takeaway
Drinking red millet yellow wine can help keep your heart healthy because it has special proteins that protect your heart cells from damage.
Methodology
The study used a solvent precipitation method to extract peptides from red millet yellow wine and tested their effects on H9c2 cardiac cells exposed to oxidative stress.
Limitations
The study primarily focused on in vitro models, which may not fully represent in vivo effects.
Statistical Information
P-Value
p<0.001
Statistical Significance
p<0.001
Digital Object Identifier (DOI)
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