5-Chloro-1-(4-methoxybenzyl)indoline-2,3-dione
2011
Structure of 5-Chloro-1-(4-methoxybenzyl)indoline-2,3-dione
publication
Evidence: moderate
Author Information
Author(s): Wu Weiyao, Zheng Tingting, Cao Shengli, Xiao Zhichang
Primary Institution: Capital Normal University, Beijing, People’s Republic of China
Hypothesis
To explore the structure of the title compound and its potential antitumor activity.
Conclusion
The study successfully synthesized and characterized the compound, revealing its three-dimensional framework and intermolecular interactions.
Supporting Evidence
- The compound was synthesized with a yield of 72%.
- Intermolecular interactions were characterized, including C—H···O and π–π stacking.
- The dihedral angle between the benzene ring and the indole moiety was measured at 88.44°.
Takeaway
The researchers made a new chemical compound and looked at how its parts fit together, which could help in fighting cancer.
Methodology
The compound was synthesized through a reaction involving 5-chloro-indoline-2,3-dione and 4-methoxybenzyl chloride, followed by purification.
Digital Object Identifier (DOI)
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