Development of a questionnaire to measure health-related quality of life (HRQoL) in patients with atrial fibrillation (AF-QoL)
2007

Development of a Questionnaire for Atrial Fibrillation Patients' Quality of Life

Sample size: 112 publication Evidence: moderate

Author Information

Author(s): Badia Xavier, Arribas Fernando, Ormaetxe Jose Miguel, Peinado Rafael, de los Terreros Miguel Sainz

Primary Institution: IMS Health

Hypothesis

The study aims to develop a health-related quality of life (HRQoL) questionnaire specifically for patients with atrial fibrillation.

Conclusion

An initial HRQoL questionnaire, AFQoL-18, has been developed to assess HRQoL in AF patients.

Supporting Evidence

  • The study identified 10 domains affecting HRQoL in AF patients.
  • A total of 286 items were identified and reduced to 40 for the preliminary questionnaire.
  • The AF-QoL-18 questionnaire was developed based on patient feedback and statistical analysis.

Takeaway

Researchers created a new questionnaire to help understand how atrial fibrillation affects patients' daily lives.

Methodology

The study involved a literature review, focus groups with cardiologists, and interviews with patients to develop and test a preliminary questionnaire.

Potential Biases

Potential bias from non-self-administered questionnaires and the focus on symptomatic patients.

Limitations

The study's methodology for assessing HRQoL in AF patients was not standardized, and the sample may not represent all AF patients.

Participant Demographics

Mean age was 60.52 years, with 64.3% male and 52.7% having paroxysmal AF.

Statistical Information

P-Value

p<0.01

Statistical Significance

p<0.01

Digital Object Identifier (DOI)

10.1186/1477-7525-5-37

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