Unveiling Hidden Allies: In Silico Discovery of Prophages in Tenacibaculum Species
2024

Discovering Prophages in Tenacibaculum Species for Phage Therapy

Sample size: 212 publication 10 minutes Evidence: moderate

Author Information

Author(s): Ramírez Carolina, Romero Jaime

Primary Institution: Laboratorio de Biotecnología de Alimentos, Instituto de Nutrición y Tecnología de los Alimentos (INTA), Universidad de Chile

Hypothesis

Can prophages in Tenacibaculum species be identified and utilized for phage therapy in aquaculture?

Conclusion

Key prophage elements in Tenacibaculum, especially in T. maritimum, show promise for phage therapy against tenacibaculosis, supporting sustainable, antibiotic-free treatments in aquaculture.

Supporting Evidence

  • 25 phage elements were identified in 24 out of 212 analyzed genomes.
  • 11% of the assemblies contained phage elements.
  • Six of the identified elements were classified as intact.

Takeaway

Scientists found special virus parts in certain bacteria that can help fight fish diseases without using antibiotics, which is good for fish health.

Methodology

The study analyzed 212 Tenacibaculum genomes using the PHASTEST program to identify prophages and evaluated their characteristics.

Limitations

The study may not cover all Tenacibaculum species and relies on available genomic data, which may not represent all strains.

Digital Object Identifier (DOI)

10.3390/antibiotics13121184

Want to read the original?

Access the complete publication on the publisher's website

View Original Publication