Comparative phylogenomic analyses of teleost fish Hox gene clusters: lessons from the cichlid fish Astatotilapia burtoni: comment
2008
Reanalysis of HoxC1a Gene in Cichlid Fish
Commentary
Evidence: moderate
Author Information
Author(s): Thomas-Chollier Morgane, Ledent Valérie
Primary Institution: Université Libre de Bruxelles
Hypothesis
The HoxC1a gene was lost twice independently in Neoteleosts.
Conclusion
The study identifies a putative HoxC1a gene in Astatotilapia burtoni and suggests independent gene loss events in teleosts.
Supporting Evidence
- The study complements previous findings by identifying a putative HoxC1a gene in Astatotilapia burtoni.
- Phylogenetic analyses support the presence of HoxC1a in multiple teleost species.
- Evidence suggests that HoxC1a was lost independently in different teleost lineages.
Takeaway
Scientists looked at a fish's genes and found one that was thought to be missing. They think it disappeared in some fish but not in others.
Methodology
The study used a combination of sequence similarity methods, de-novo gene predictions, and a specialized program for Hox protein classification.
Limitations
The study relies on predictions and may not have experimental validation for all findings.
Digital Object Identifier (DOI)
Want to read the original?
Access the complete publication on the publisher's website