Genetic Characterization of a New Bluetongue Virus from Goats in Switzerland
Author Information
Author(s): Hofmann Martin A., Renzullo Sandra, Mader Markus, Chaignat Valérie, Worwa Gabriella, Thuer Barbara
Primary Institution: Institute of Virology and Immunoprophylaxis, Mittelhaeusern, Switzerland
Hypothesis
Is Toggenburg orbivirus a new serotype of bluetongue virus?
Conclusion
The study identifies Toggenburg orbivirus as a likely new 25th serotype of bluetongue virus.
Supporting Evidence
- Toggenburg orbivirus was detected in goats using specific PCR methods.
- Sequencing showed that TOV is closely related to known bluetongue virus serotypes.
- Phylogenetic analysis placed TOV within the BTV serogroup but distinct from known serotypes.
Takeaway
Scientists found a new type of bluetongue virus in goats in Switzerland, which is different from the known types.
Methodology
The virus was detected using real-time reverse transcription–PCR, and its genome was sequenced and analyzed.
Limitations
The study did not confirm the presence of the virus in all tested animals, and the viral load was low.
Participant Demographics
Goats from a herd in northeastern Switzerland.
Digital Object Identifier (DOI)
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