High Mortality in Patients with Alcoholic Liver Disease and High Serum Creatinine
Author Information
Author(s): Whiteside A, Whiting P
Primary Institution: Sheffield Teaching Hospitals NHS Trust
Hypothesis
Is raised serum creatinine at admission to critical care associated with increased mortality in patients with decompensated alcoholic liver disease?
Conclusion
Patients with a serum creatinine of 150 mmol/l or greater at admission have a 94% mortality rate.
Supporting Evidence
- Hospital mortality rate was 45%.
- Six-month mortality rate was 49%.
- One-year mortality rate was 51%.
- 94% of patients with high serum creatinine died during their hospital stay.
Takeaway
If someone with liver problems has very high kidney levels when they go to the hospital, they are very likely to not survive.
Methodology
A retrospective cohort study of patients with decompensated alcoholic liver disease admitted to critical care over a 3-year period.
Limitations
The study only included patients from two hospitals and may not be generalizable.
Participant Demographics
Patients with decompensated alcoholic liver disease, ages around 50.
Statistical Information
P-Value
0.9
Statistical Significance
p=0.9
Digital Object Identifier (DOI)
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