Predictors of successful treatment in patients receiving intra-articular injections of hylan G-F 20 or saline for painful first MTPJ OA
2011

Predictors of Successful Treatment for First MTPJ Osteoarthritis

Sample size: 151 publication Evidence: moderate

Author Information

Author(s): Munteanu Shannon, Zammit Gerard V, Menz Hylton B

Primary Institution: La Trobe University

Hypothesis

Can we identify predictors of treatment success in patients with first MTPJ OA receiving intra-articular injections?

Conclusion

Patients without definite radiographic first MTPJ OA are more likely to report success from intra-articular injections.

Supporting Evidence

  • 42% of participants reported treatment success at 12 weeks.
  • Increased FHSQ foot function was a predictor of treatment success.
  • Absence of definite radiographic OA was associated with higher treatment success.

Takeaway

This study looked at how to tell if a treatment for foot pain will work. It found that if you don't have clear signs of joint damage, you're more likely to feel better after the treatment.

Methodology

Participants received either hylan G-F 20 or saline injections, and various predictors were analyzed using univariate and multivariate logistic regression.

Limitations

The study may not account for all potential predictors of treatment success.

Statistical Information

P-Value

p=0.027

Confidence Interval

95% CI 1.11 to 3.13

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1186/1757-1146-4-S1-P42

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