Inappropriate Use of IV PPI for Stress Ulcer Prevention
Author Information
Author(s): Perwaiz Muhammad K., Posner Gerald, Hammoudeh Fadi, Schmidt Frances, Neupane Narayan, Enriquez Danilo, Gulati Neerja
Primary Institution: Interfaith Medical Center, Brooklyn, NY, USA
Hypothesis
The study aims to measure the inappropriate use of intravenous proton pump inhibitors (IV PPIs) for stress ulcer prophylaxis and estimate the financial burden.
Conclusion
A more rational use of PPI will have better impact on health care cost and is likely to add to patient safety.
Supporting Evidence
- 68.5% of patients received IV PPI without a proper indication.
- The estimated cost of inappropriate IV PPI use was $18,337.
- Patients discharged on PPI prescriptions often lacked proper indications.
Takeaway
Doctors are giving too many patients IV medications to prevent stomach ulcers when they don't really need them, which costs a lot of money.
Methodology
A retrospective, analytic study using hospital pharmacy records to identify patients who received IV PPI during their stay.
Potential Biases
There may be a risk of bias due to the reliance on chart reviews and the exclusion of patients already on PPI prior to admission.
Limitations
The study did not include outpatient PPI use and could not determine the exact number of patients discharged on inappropriate PPI prescriptions.
Participant Demographics
{"mean_age":59,"sex_distribution":{"female":52.4,"male":48.6},"race_distribution":{"black":80,"hispanic":5.3,"white":7.3,"asian":2.9,"others":3}}
Digital Object Identifier (DOI)
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