Red Blood Cell Antibody Screening in Pregnancy
Author Information
Author(s): Devi Shanthala A. M., Alwar Vanamala A., Sitalakshmi S., Rameshkumar Karuna Mhaskar Rita
Primary Institution: St Johns Medical College Hospital, Bangalore, India
Hypothesis
Can red cell antibody screening effectively identify alloantibodies in pregnant women?
Conclusion
Red cell antibody screening is a valuable tool for detecting alloantibodies during pregnancy, with anti-D being the most common antibody identified.
Supporting Evidence
- Red cell antibody screening was positive in 1.4% of cases.
- Anti-D was identified in 66% of positive cases.
- Anti-M antibodies can cause hemolytic disease of the newborn, although they are rare.
Takeaway
Doctors can check pregnant women for certain antibodies that might cause problems for their babies, and they found that one type of antibody, called anti-D, is the most common.
Methodology
A prospective study using a 3-cell panel for red cell antibody screening and identification.
Participant Demographics
Antenatal cases from St Johns Medical College Hospital, Bangalore, India.
Digital Object Identifier (DOI)
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