JC and BK virus sequences are not detectable in leukaemic samples from children with common acute lymphoblastic leukaemia
1999

No JC and BK Virus Found in Children's Leukaemia Samples

publication

Author Information

Author(s): MacKenzie J, Perry J, Ford A M, Jarrett R F, Greaves M

Primary Institution: LRF Virus Centre, Department of Veterinary Pathology, University of Glasgow

Hypothesis

Can JC and BK virus genomes be detected in leukaemic cells from children with common acute lymphoblastic leukaemia?

Conclusion

The study found no evidence that JC virus plays a direct role in causing leukaemia in children.

Supporting Evidence

  • Epidemiological evidence suggests that childhood leukaemia may have an infectious cause.
  • The study did not find JC or BK virus genomes in the leukaemic samples.

Takeaway

The researchers looked for certain viruses in children's leukaemia samples and didn't find them, suggesting these viruses aren't causing the disease.

Methodology

The study investigated the presence of JC and BK virus genomes in leukaemic cells.

Digital Object Identifier (DOI)

10.1038/sj.bjc.6690783

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