Radiotherapy for Stage I Hodgkin's Disease: 20 Years Experience
Author Information
Author(s): T.S. Ganesan, P.F.M. Wrigley, P.A. Murray, A.G. Stansfeld, A.J. d'Ardenne, S. Arnott, A. Jones, W.S. Shand, J.S. Malpas, T.A. Lister
Primary Institution: St Bartholomew's Hospital
Conclusion
The study shows that patients with stage I Hodgkin's disease treated with radiotherapy have a good prognosis, with a significant number remaining in remission after 15 years.
Supporting Evidence
- Complete remission was achieved in all evaluable patients.
- Actuarial overall survival in these 90 patients was 75% at 15 years.
- Factors predictive of a prolonged remission included pathological staging and lymph node size.
Takeaway
Doctors treated 101 patients with a type of cancer called Hodgkin's disease, and most of them got better and stayed healthy for a long time.
Methodology
Patients received either mantle or inverted 'Y' radiotherapy, and their outcomes were analyzed over a median follow-up of 12 years.
Limitations
The study only included patients treated at one hospital and may not be generalizable to all patients with Hodgkin's disease.
Participant Demographics
The median age of participants was 33 years, with 72 men and 29 women.
Statistical Information
P-Value
0.02
Statistical Significance
p=0.02
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