1-(3-Fluorophenyl)-4,4,6-trimethyl-3,4-dihydropyrimidine-2(1H)-thione
2011
Study of a New Compound: 1-(3-Fluorophenyl)-4,4,6-trimethyl-3,4-dihydropyrimidine-2(1H)-thione
publication
Author Information
Author(s): Yamin Bohari M., Lawi Ruhana L., Salem Halima F.
Primary Institution: School of Chemical Sciences and Food Technology, Universiti Kebangsaan Malaysia
Conclusion
The compound exhibits a planar dihydropyrimidine ring and forms centrosymmetric dimers through hydrogen bonding.
Supporting Evidence
- The dihydropyrimidine ring is essentially planar with a maximum deviation of 0.086 Å.
- The benzene ring is almost perpendicular to the dihydropyrimidine ring with a dihedral angle of 83.97°.
- The crystal packing is characterized by centrosymmetric dimers resulting from pairs of intermolecular N—H⋯S hydrogen bonds.
Takeaway
Scientists studied a new chemical compound that has a special structure and can form pairs with itself through bonds.
Methodology
The compound was synthesized using equimolar quantities of thiocyanic acid and 3-fluoroaniline in acetone, followed by crystallization.
Digital Object Identifier (DOI)
Want to read the original?
Access the complete publication on the publisher's website