Repeated Assessment of Exploration and Novelty Seeking in the Human Behavioral Pattern Monitor in Bipolar Disorder Patients and Healthy Individuals
2011

Exploration and Novelty Seeking in Bipolar Disorder

Sample size: 33 publication Evidence: moderate

Author Information

Author(s): Arpi Minassian, Henry Brook, Jared W. Young, Virginia Geyer, Mark A. Perry, William Scott

Primary Institution: Department of Psychiatry, University of California San Diego

Hypothesis

Bipolar disorder individuals will show heightened motor activity and novel object exploration compared to healthy volunteers over repeated testing.

Conclusion

Manic BD patients showed a modest reduction in symptoms yet still demonstrated hyper-exploration and novelty seeking, suggesting these features may be enduring characteristics of the disorder.

Supporting Evidence

  • Manic BD patients showed greater motor activity than healthy volunteers.
  • Exploration and novelty-seeking decreased in manic BD subjects over sessions but remained higher than healthy volunteers.
  • Healthy volunteers did not show significant decreases in exploration over time.

Takeaway

People with bipolar disorder tend to explore more and seek new things, even when they start feeling better. This study shows that these behaviors don't go away quickly with treatment.

Methodology

The study involved 12 manic BD patients and 21 healthy volunteers tested in a human Behavioral Pattern Monitor over three sessions.

Potential Biases

The study's naturalistic design and varied medications among BD patients may introduce confounding factors.

Limitations

The small sample size of BD patients limits the generalizability of the findings.

Participant Demographics

12 manic BD patients (6 male) aged 18-55 and 21 healthy volunteers (11 male).

Statistical Information

P-Value

p=0.002

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1371/journal.pone.0024185

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