Effects of Folk Herbs on Male Rat Fertility
Author Information
Author(s): Khalaf Rana R., Khazaal Salma, Abouzeinab Noura S., Khalil Mahmoud I., Mititelu Magdalena, Manolescu Bogdan, Oprea Eliza
Primary Institution: Beirut Arab University
Hypothesis
The study aims to explore the impact of selected folk herbs on the fertility of male Sprague Dawley rats.
Conclusion
The study found that the herbal extracts, especially the mixture, enhance fertility by stimulating spermatogenesis.
Supporting Evidence
- OM and MIX showed the highest total phenolic content and antioxidant activities.
- Elevated serum testosterone and sperm concentration were observed in all groups, especially in the MIX group.
- Histomorphometric parameters were significantly improved in the MIX group.
- Vimentin and mTOR expression levels were elevated in the testes of treated rats.
Takeaway
This study shows that certain plants can help male rats have more babies by improving their sperm health.
Methodology
The study involved administering aqueous extracts of selected herbs to male rats and measuring various fertility parameters over 60 days.
Potential Biases
The study was conducted in a blinded manner to avoid bias.
Limitations
The study duration was limited to 60 days, and only testicular histology was examined.
Participant Demographics
28 healthy adult male Sprague Dawley rats aged 6-7 weeks.
Statistical Information
P-Value
p<0.001
Confidence Interval
95%
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
Want to read the original?
Access the complete publication on the publisher's website