Hereditary dentine disorders: dentinogenesis imperfecta and dentine dysplasia
2008
Hereditary Dentine Disorders: Dentinogenesis Imperfecta and Dentine Dysplasia
publication
Evidence: moderate
Author Information
Author(s): Barron Martin J, McDonnell Sinead T, MacKie Iain, Dixon Michael J
Primary Institution: University of Manchester
Conclusion
Early diagnosis and treatment of hereditary dentine disorders can lead to good aesthetics and function.
Supporting Evidence
- Dentinogenesis imperfecta (DGI) has an incidence of 1 in 6,000 to 1 in 8,000.
- Dentine dysplasia (DD) type 1 has an incidence of 1 in 100,000.
- Diagnosis is based on family history, clinical examination, and may include genetic testing.
Takeaway
Some people have teeth that are weak and discolored because of genetic conditions. If doctors find these problems early, they can help fix them.
Methodology
The review discusses the classification, diagnosis, and treatment of hereditary dentine disorders based on clinical features and genetic studies.
Limitations
The classification of these disorders is complicated and may change as more genetic mutations are discovered.
Digital Object Identifier (DOI)
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