Enteral Feeding in Patients With Open Abdomen and Negative Pressure Therapy
Author Information
Author(s): Laurent Petit, Nicolas Faure, Bruno Pereira, Vincent Dubuisson, Xavier Berard, Matthieu Biais, Cédric Carrié
Primary Institution: Pellegrin University Hospital, Bordeaux, France
Hypothesis
The study aims to assess the effect of enteral nutritional support during the acute phase on clinical outcomes in critically ill surgical patients treated by open abdomen and negative pressure therapy.
Conclusion
In critically ill patients with open abdomen and negative pressure therapy, the use of enteral feeding within 7 days after surgery was associated with better clinical outcomes.
Supporting Evidence
- 50% of patients experienced delayed abdominal closure or secondary complications.
- The rate of complications was significantly lower in patients receiving enteral nutrition compared to those who did not.
- The study suggests that enteral feeding should be initiated as soon as possible after surgery.
Takeaway
Feeding patients through a tube in their stomach after surgery helps them heal better and have fewer complications.
Methodology
This retrospective cohort study included critically ill patients treated by open abdomen and negative pressure therapy over a 5-year period, analyzing the impact of enteral nutrition on clinical outcomes.
Potential Biases
Potential unrecorded confounders may affect the observed associations.
Limitations
The study's retrospective design may lead to selection and interpretation bias, and it was underpowered to assess the effect of high protein intake.
Participant Demographics
The study included adult critically ill surgical patients with a mean age of 63 years, predominantly male (81%).
Statistical Information
P-Value
0.007
Confidence Interval
[95%CI: 0.25–0.98]
Statistical Significance
p = 0.007
Digital Object Identifier (DOI)
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