Toxic epidermal necrolysis associated with severe cytomegalovirus infection in a patient on regular hemodialysis
2011

Toxic Epidermal Necrolysis Linked to Cytomegalovirus Infection in a Dialysis Patient

Sample size: 1 publication Evidence: low

Author Information

Author(s): Khalaf Dina, Toema Bassem, Dabbour Nidal, Jehani Fathi

Primary Institution: Cairo University, Egypt

Hypothesis

Is there a link between toxic epidermal necrolysis and fulminant cytomegalovirus infection?

Conclusion

The study suggests a possible association between toxic epidermal necrolysis and cytomegalovirus reactivation in an immunocompromised patient.

Supporting Evidence

  • The patient had a confirmed diagnosis of cytomegalovirus esophagitis and duodenitis.
  • Skin biopsy confirmed toxic epidermal necrolysis.
  • Despite treatment, the patient's condition deteriorated rapidly.

Takeaway

A woman with a severe skin reaction may have had it because of a virus that usually stays hidden in the body, especially since she was already very sick.

Methodology

Case report detailing the patient's symptoms, diagnosis, and treatment.

Potential Biases

Potential bias due to the anecdotal nature of the case report.

Limitations

Only one case is reported, limiting the generalizability of the findings.

Participant Demographics

A 50-year-old Caucasian female with diabetes, hypertension, and end-stage renal disease.

Digital Object Identifier (DOI)

10.4084/MJHID.2011.004

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