Surgical Outcomes for Upper Urinary Tract Cancer: Comparing Two Techniques
Author Information
Author(s): Taweemonkongsap Tawatchai, Nualyong Chaiyong, Amornvesukit Teerapon, Leewansangtong Sunai, Srinualnad Sittiporn, Chaiyaprasithi Bansithi, Sujijantararat Phichaya, Tantiwong Anupan, Soontrapa Suchai
Primary Institution: Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand
Hypothesis
Is retroperitoneoscopic nephroureterectomy (RNU) as effective as open nephroureterectomy (ONU) for treating upper urinary tract transitional cell carcinoma (TCC)?
Conclusion
Retroperitoneoscopic nephroureterectomy is less invasive than open surgery and is an oncological feasible operation.
Supporting Evidence
- The mean operative time was longer in the RNU group than in the ONU group (258.8 vs. 190.6 min; p < 0.001).
- The mean blood loss was lower in the RNU group (289.3 ml vs. 313.7 ml; p = 0.868).
- Complications occurred in 2 patients in each group.
- Bladder cancer recurrence occurred in 9 patients (29%) in the RNU group and 13 patients (44.8%) in the ONU group.
Takeaway
Doctors compared two types of surgery for kidney cancer. One type is less invasive and still works well.
Methodology
Retrospective analysis of 60 patients who underwent nephroureterectomy for upper tract TCC, comparing outcomes between RNU and ONU.
Potential Biases
Potential selection bias due to surgeon's preference for surgical technique.
Limitations
Retrospective study design may limit the reliability of the findings.
Participant Demographics
Patients included 31 treated with RNU and 29 with ONU, with a mean age of 63.8 years for RNU and 66.8 years for ONU.
Statistical Information
Confidence Interval
95% CI = 0.67, 3.35
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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