Astragalus-based Eefooton for Chronic Kidney Disease
Author Information
Author(s): Lu Kuo-Cheng, Kuo Ko-Lin, Wu San-Chiang, Lin Chih-Hui, Lin Cheng-Ju, Hou Yi-Chou, Chen Jin-Shuen
Primary Institution: Kaohsiung Veterans General Hospital
Hypothesis
Can Eefooton, a Traditional Chinese Medicine, improve kidney function in patients with chronic kidney disease?
Conclusion
Eefooton treatment significantly improved kidney function in patients with stage 3-5 chronic kidney disease without safety concerns.
Supporting Evidence
- Median eGFR improved from 34.37 to 42.47 mL/min/1.73 m2 after treatment.
- Improvements were statistically significant across different CKD stages.
- Ultrasonography showed a slight increase in kidney size after treatment.
Takeaway
This study shows that a herbal medicine called Eefooton can help people with kidney problems feel better and improve their kidney function.
Methodology
A self-controlled, prospective study with 75 stage 3-5 CKD patients receiving Eefooton treatment for six months, alongside conventional medications.
Potential Biases
Potential biases due to the non-randomized design and self-selection of participants.
Limitations
The study had a limited sample size and did not measure proteinuria changes.
Participant Demographics
75 patients (33 females, 42 males; mean age 68.20 years) with stage 3-5 CKD.
Statistical Information
P-Value
p<0.001
Statistical Significance
p<0.001
Digital Object Identifier (DOI)
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