Rebleeding rate after interventional therapy directed by capsule endoscopy in patients with obscure gastrointestinal bleeding
2008

Rebleeding Rates After Capsule Endoscopy in Patients with Obscure Gastrointestinal Bleeding

Sample size: 77 publication Evidence: moderate

Author Information

Author(s): Endo Hiroki, Matsuhashi Nobuyuki, Inamori Masahiko, Akimoto Keiko, Ohya Tomohiko, Yanagawa Tatsuro, Asayama Masako, Hisatomi Kantaro, Teratani Takuma, Fujita Koji, Yoneda Masato, Nakajima Atsushi

Primary Institution: Yokohama City University School of Medicine

Hypothesis

Which management strategies after capsule endoscopy reduce rebleeding in patients with obscure gastrointestinal bleeding?

Conclusion

Follow-up and further aggressive interventions are necessary for patients with obscure gastrointestinal bleeding and significant capsule endoscopy findings to reduce the chance of rebleeding.

Supporting Evidence

  • Capsule endoscopy identified significant findings in 58.4% of patients.
  • The overall rebleeding rate was 36.4%.
  • Patients with significant findings had a lower rebleeding rate if they underwent therapeutic interventions (9.5% vs 40.0%).
  • Rebleeding was significantly higher among patients with insignificant findings.
  • Most rebleeding occurred within the first 6 months after capsule endoscopy.

Takeaway

Doctors used a special camera to look inside patients' bellies to find out why they were bleeding. They found that if they did more treatments after finding something wrong, the patients were less likely to bleed again.

Methodology

The study evaluated the clinical outcomes of patients with obscure gastrointestinal bleeding after capsule endoscopy, focusing on the rebleeding rate as the primary outcome.

Potential Biases

The study may be biased as the authors tended to follow up their own patients more accurately.

Limitations

The study was not a randomized trial, and follow-up data from other hospitals were often incomplete.

Participant Demographics

{"gender":{"male":54,"female":23},"mean_age":58.4,"mean_hemoglobin":7.7,"mean_follow_up_period":11.6}

Statistical Information

P-Value

0.036

Statistical Significance

p = 0.036

Digital Object Identifier (DOI)

10.1186/1471-230X-8-12

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