Is an aggressive approach justified in the management of an aggressive cancer-the squamous cell carcinoma of thyroid?
2007

Management of Squamous Cell Carcinoma of the Thyroid

Sample size: 3 publication Evidence: low

Author Information

Author(s): Chintamani, Kulshreshtha Pranjal, Singh Jaiprakash, Sugandhi Nidhi, Bansal Anju, Bhatnagar Dinesh, Saxena Sunita

Primary Institution: Vardhman Mahavir Medical College, Safdarjang Hospital, New Delhi, India

Hypothesis

Is an aggressive approach justified in the management of an aggressive cancer-the squamous cell carcinoma of thyroid?

Conclusion

Primary squamous cell carcinoma is a rare malignancy with a poor outcome despite combined modality therapy.

Supporting Evidence

  • Primary squamous cell carcinoma of the thyroid is extremely rare, with less than 50 cases reported worldwide.
  • The prognosis for this cancer is poor, with a median survival of less than six months.
  • Two out of three patients in this study died within a year despite treatment.

Takeaway

This study looked at three patients with a rare type of thyroid cancer that grows quickly and is hard to treat. Even with surgery and radiation, two of the patients died within a year.

Methodology

The study involved case reports of three patients diagnosed with primary squamous cell carcinoma of the thyroid, detailing their clinical presentation, treatment, and outcomes.

Limitations

The study is based on a small number of cases, which limits the generalizability of the findings.

Participant Demographics

Two males and one female, aged between 50 and 60 years.

Digital Object Identifier (DOI)

10.1186/1477-7800-4-8

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