Does comorbidity explain the ethnic inequalities in cervical cancer survival in New Zealand? A retrospective cohort study
2011

Ethnic Inequalities in Cervical Cancer Survival in New Zealand

Sample size: 1594 publication 10 minutes Evidence: moderate

Author Information

Author(s): Naomi Brewer, Barry Borman, Diana Sarfati, Mona Jeffreys, Steven T Fleming, Soo Cheng, Neil Pearce

Primary Institution: Centre for Public Health Research, Massey University

Hypothesis

Does comorbidity explain the ethnic inequalities in cervical cancer survival in New Zealand?

Conclusion

Comorbidity is associated with cervical cancer-specific survival in New Zealand, but accounts for only a moderate proportion of the ethnic differences in survival.

Supporting Evidence

  • Comorbidity during the year before diagnosis was associated with cervical cancer-specific survival.
  • Those with an Elixhauser count of ≥3 had a hazard ratio of 2.17.
  • Adjustment for individual comorbid conditions reduced the excess risk of Māori and Pacific women.

Takeaway

Women with other health problems (comorbidities) have a harder time surviving cervical cancer, but these problems don't fully explain why some ethnic groups do worse than others.

Methodology

The study analyzed 1,594 cervical cancer cases registered from 1994 to 2005, using Cox regression to estimate mortality hazard ratios based on comorbidity data.

Potential Biases

Misclassification of ethnicity could dilute observed survival differences between groups.

Limitations

Potential misclassification of ethnicity and comorbidity data based on administrative records may affect results.

Participant Demographics

73% identified as 'Other' ethnicity, 18% as Māori, 4% as Pacific, and 5% as Asian.

Statistical Information

P-Value

0.0001

Confidence Interval

1.32-3.56

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1186/1471-2407-11-132

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