Comparison of maintenance and emergence characteristics after desflurane or sevoflurane in outpatient anaesthesia
2011

Comparing Desflurane and Sevoflurane in Outpatient Anaesthesia

Sample size: 100 publication Evidence: moderate

Author Information

Author(s): Jindal Ravi, Kumra Ved Prakash, Narani Krishan Kumar, Sood Jayashree

Primary Institution: Sir Ganga Ram Hospital, New Delhi, India

Hypothesis

Does desflurane provide faster recovery compared to sevoflurane in outpatient anaesthesia?

Conclusion

Desflurane leads to faster emergence from anaesthesia than sevoflurane, but does not result in earlier readiness for home discharge.

Supporting Evidence

  • Desflurane resulted in significantly shorter response times to painful stimuli and verbal commands compared to sevoflurane.
  • Patients given desflurane achieved a Modified Aldrete Score of 9 significantly faster than those given sevoflurane.
  • Both anaesthetics provided similar intraoperative haemodynamic stability.

Takeaway

This study found that patients wake up faster with desflurane than with sevoflurane, but both groups are ready to go home at about the same time.

Methodology

A randomized, prospective, single-blind study involving 100 female patients undergoing daycare laparoscopic gynaecological surgery.

Potential Biases

Potential bias due to the non-blinded nature of the study.

Limitations

The study design did not allow for a double-blind comparison, and a cost analysis was not included.

Participant Demographics

100 female patients, ASA grade I or II, scheduled for short daycare gynaecological procedures.

Statistical Information

P-Value

0.000

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.4103/0019-5049.76604

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