A genomic approach to identifying and classifying yeast genes involved in cell wall formation and its regulation
2001

Identifying Yeast Genes for Cell Wall Formation

Sample size: 620 publication

Author Information

Author(s): de Groot, Woods, Oliver Fiehn, Andrew Simpson, Duncan Campbell, Philip Masterson

Conclusion

The study systematically screened yeast genes to identify those involved in cell wall formation and regulation.

Supporting Evidence

  • 145 mutants showing at least one phenotype were selected for further screening.
  • The study refined the gene set of Saccharomyces cerevisiae.
  • New methods for understanding metabolic networks were discussed.

Takeaway

Researchers looked at many yeast genes to find out which ones help make the cell wall and how they work together.

Methodology

The study involved screening non-essential single-gene yeast deletants for cell wall-related phenotypes.

Digital Object Identifier (DOI)

10.1002/cfg.84

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