Should the first degree relatives of type 2 diabetic patients with isolated impaired fasting glucose be considered for a diabetes primary prevention program?
2010

Diabetes Prevention for Relatives of Type 2 Diabetics

Sample size: 793 publication Evidence: moderate

Author Information

Author(s): Iraj Bijan, Taheri Nader, Amini Massoud, Amini Payvand, Aminorroaya Ashraf

Primary Institution: Isfahan University of Medical Sciences

Hypothesis

Should the first degree relatives of type 2 diabetic patients with isolated impaired fasting glucose be considered for a diabetes primary prevention program?

Conclusion

First degree relatives of T2DM with isolated impaired fasting glucose should probably be included in the primary preventive program for diabetes.

Supporting Evidence

  • The prevalence of cardiometabolic risk factors is higher in the i-IFG group than in the i-IGT group.
  • The mean level of LDL-C is significantly higher in the i-IFG than in the i-IGT group.
  • Higher BMI, weight gain, dyslipidemia, hypertension, and elevated fasting plasma glucose are predictors of progression to T2DM.

Takeaway

If your family member has diabetes and you have slightly high blood sugar, you might need to take steps to prevent getting diabetes yourself.

Methodology

A cross-sectional study comparing cardiometabolic risk factors in first degree relatives of T2DM with isolated IFG and isolated IGT.

Limitations

The study's cross-sectional nature cannot establish cause and effect, and it was not multicenter.

Participant Demographics

Participants were first degree relatives of type 2 diabetic patients, aged 35-55 years.

Statistical Information

P-Value

p<0.05

Statistical Significance

p<0.05

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