Urinary Output and Mortality in Cardiogenic Shock
Author Information
Author(s): Markart Sebastian, Hermann Alexander, Chiari Florian, Heinz Gottfried, Speidl Walter S., Lenz Max, Hengstenberg Christian, Schellongowski Peter, Staudinger Thomas, Zilberszac Robert
Primary Institution: Medical University of Vienna
Hypothesis
Can urinary output at different time intervals predict 30-day mortality in patients with cardiogenic shock?
Conclusion
Early urinary output is a valuable predictor of 30-day mortality in patients with cardiogenic shock, but its strength is limited when combined with comprehensive risk assessments like SAPS 3.
Supporting Evidence
- Urinary output at 6–12 hours was significantly associated with 30-day mortality.
- SAPS 3 had a higher predictive value for mortality compared to urinary output.
- Patients producing less than 0.5 mL/kg/h of urine had significantly worse survival outcomes.
Takeaway
This study found that how much urine patients produce in the first hours of cardiogenic shock can help doctors predict if they will survive, but it's not the only thing to look at.
Methodology
Retrospective analysis of 96 patients with cardiogenic shock, assessing urinary output at different intervals and comparing it to SAPS 3.
Potential Biases
Potential biases due to the retrospective nature and exclusion of patients with incomplete data.
Limitations
The study is retrospective and may be affected by confounding factors; it also lacks advanced hemodynamic measurements.
Participant Demographics
Predominantly male (71.9%), median age 65 years, with various comorbidities including hypertension and diabetes.
Statistical Information
P-Value
p < 0.001 for SAPS 3
Confidence Interval
CI 0.67–0.87 for SAPS 3
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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