PREDICTORS OF CHANGE IN CAROTID ARTERY ULTRASOUND MEASURES IN THE LONG LIFE FAMILY STUDY
2024

Predictors of Change in Carotid Artery Ultrasound Measures

Sample size: 674 publication Evidence: moderate

Author Information

Author(s): Kuipers Allison, Kline Caitlyn, Cvejkus Ryan, Barinas-Mitchell Emma, Zmuda Joseph

Primary Institution: University of Pittsburgh

Hypothesis

The study aims to identify predictors of change in carotid intima-media thickness and interadventitial diameter over time.

Conclusion

The study found that age, sex, and certain health factors significantly influence changes in carotid artery measurements over time.

Supporting Evidence

  • IMT increased 0.046mm or 1.08% annually.
  • IAD increased 0.166mm or 0.37% annually.
  • IMT APCT change was greater in those aged < 65 than over 65.
  • IAD APCT change was greater in females than males.

Takeaway

This study looked at how different factors affect the health of blood vessels over time in older people.

Methodology

Carotid ultrasound was conducted, and changes in measurements were analyzed using linear regression models.

Participant Demographics

Participants were aged 67.5 years on average, with 43% male, 35% hypertensive, and 6% diabetic.

Statistical Information

P-Value

P=0.004

Statistical Significance

p<0.0001

Digital Object Identifier (DOI)

10.1093/geroni/igae098.3298

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