Treatment of Liver Metastasis from Gastric Cancer
Author Information
Author(s): Ojima Hitoshi, Ootake Sayaka, Yokobori Takehiko, Mochida Yasushi, Hosouchi Yasuo, Nishida Yasuji, Kuwano Hiroyuki
Primary Institution: Gunma Prefecture Saiseikai-Maebashi Hospital
Hypothesis
Is hepatic arterial infusion (HAI) effective for treating synchronous liver metastasis from gastric cancer?
Conclusion
HAI is effective for controlling liver metastasis but does not improve survival rates, which depend on the possibility of gastrectomy.
Supporting Evidence
- The response rate of HAI was 83%.
- Median survival time was 19.2 months for the HAI group.
- All patients in the HAI group underwent gastrectomy.
Takeaway
Doctors tried a new way to give medicine directly to the liver for patients with stomach cancer that spread to the liver, and it worked well to control the cancer but didn't help them live longer.
Methodology
Retrospective analysis of 37 patients with synchronous liver metastases from gastric cancer treated with HAI and other therapies.
Potential Biases
Potential selection bias due to retrospective nature and exclusion of certain patients.
Limitations
The study did not evaluate the effect of HAI on quality of life and had a small sample size.
Participant Demographics
37 patients (30 males, 7 females; mean age 70.5 years).
Statistical Information
P-Value
0.0120
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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