Efficacy of Hyaluronan for Hallux Limitus Treatment
Author Information
Author(s): Munteanu Shannon E, Menz Hylton B, Zammit Gerard V, Landorf Karl B, Handley Christopher J, ElZarka Ayman, DeLuca Jason
Primary Institution: La Trobe University
Hypothesis
Does intra-articular hyaluronan (Synvisc®) reduce pain and improve function in people with hallux limitus?
Conclusion
This study aims to evaluate the effectiveness of intra-articular hyaluronan for treating osteoarthritis of the first metatarsophalangeal joint.
Supporting Evidence
- The study is the first randomized controlled trial to evaluate hyaluronan for hallux limitus.
- Previous studies lacked a placebo control group, which this study addresses.
- The sample size is designed to provide sufficient power to detect clinically significant differences.
Takeaway
This study is testing if a special injection can help people with foot pain feel better and move easier.
Methodology
Participants will receive either hyaluronan or saline injections and will be assessed for pain and function at multiple time points.
Potential Biases
There is a risk of bias due to the injector being aware of the treatment being administered.
Limitations
The study may be limited by the potential for a placebo effect and the lack of blinding for the injector.
Participant Demographics
Community-dwelling men and women aged 18 and over with hallux limitus.
Statistical Information
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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